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latent autoimmune diabetes

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Posted: 09/25/07 - 04:39
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gard
Joined: 10 Nov 2003

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My father has a lot of problems with the diabetes. He is taking insulin every day for a long time. Now he has a new diagnose; latent autoimmune diabetes. At least that is what we have been told by a doctor. What is it? How autoimmune process can influence on diabetes?


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Posted: 10/26/07 - 20:53
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hildegarde
Joined: 11 Dec 2006

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Individuals with a genetic predisposition are exposed to an immunologic trigger that initiates an autoimmune process, resulting in a gradual decline in beta cell mass. The downward slope of the beta cell mass varies among individuals. This progressive impairment in insulin release results in diabetes when 80% of the beta cell mass is destroyed. A "honeymoon" phase may bee seen in the first 1 or 2 years after the onset of diabetes and is associated with reduced insulin requirements.


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