Rh negative blood and pregnancy complications!!

hey, My sister is rh- and had a healthy baby boy 5 years ago. She is now pregnant again with a girl and is due at the end of next month. When she first found out she was pregnant this time she was in alot of pain. She went to the doctor and they told her that she was having an eptopic pregnancy and cut out her tube and sent it off to be tested. while waiting they gave her the rh- shot that you are supposed to get after giving birth to a baby. but come to find out.. when the results came back from the lab there wasnt a baby in the tube so she was still pregnant. Today she just found out that there is fluid build up around the baby's heart and in the baby's stomach. I was just wondering if the shot that she was given could of had any effect on the baby? Ive read some articles on hydros fitalis which causes fluid build up and is related to rh-. If anyone knows any information on that, it would be greatly appreciated. thanks -Amanda

Hi i am RH NEG and had 3 miscarriages i dont have medical aid and attend at state clinic and hospital when i was pregnant with my first born they told me i am RH NEG but nothing came of it after my baby was born i had 3 miscarriages and are currently pregnant again
it just seems that no one wants to help me and give me the shot i need after all i never got any shot.
i feel i need that shot so that all this miscarriages can stop,because i really want a nother baby and dont want to lose this one inside me,
please help me i need help 072 090 1252.

I too am Rh- (O-); the anti-D injection is called Rhophylac. This injection contains a medicine called human anti-D immunoglobulin. It is given to pregnant women who have a blood type known as rhesus negative. People whose blood type is rhesus positive (RhD positive) have a substance called D antigen on the surface of their red blood cells. People whose blood type is rhesus negative (RhD negative) are missing this antigen. Whether a person is rhesus positive or rhesus negative is determined by their genes. Having a rhesus negative blood type is not usually a problem. However, if a rhesus negative woman is pregnant and her baby is rhesus positive it may cause problems.If blood cells from a rhesus positive baby get into the rhesus negative mother's bloodstream, her blood will react as if the baby’s blood is a foreign substance and will produce antibodies against it. This is not usually a problem in a first pregnancy with a rhesus positive baby. However, the antibodies that the mother produces stay in her blood, and if she has another pregnancy with a baby who is also rhesus positive, her antibodies can cross the placenta and attack the blood cells of the unborn baby. This can cause 'haemolytic disease of the newborn'. Haemolytic disease of the newborn can be very mild, but in a small number of babies it can be more serious and cause the baby to be stillborn, severely disabled or to die after birth as a result of anaemia and jaundice.The most common time for a baby's blood cells to get into the mother's blood, causing her to produce antibodies, is at the time of birth. However, this can also occur at other times, for example during a miscarriage or abortion, or as the result of having an amniocentesis, chorionic villus sampling, vaginal bleeding, or turning the baby’s head down (external cephalic version). These events are called 'potentially sensitising events'. To prevent rhesus negative women producing antibodies against their baby’s blood during pregnancy they can be given an injection with anti-D immunoglobulin. This treatment is called anti-D prophylaxis, and prevents the mother's immune reaction that could cause haemolytic disease of the newborn.Anti-D prophylaxis is offered routinely to pregnant women who are rhesus negative, usually at weeks 28 and 34 of their pregnancy, unless they already have anti-D antibodies in their blood. (This is tested by a blood test at the start of the pregnancy.) The treatment is offered regardless of whether a sensitisation event has occurred, in order to be absolutely certain that the mother does not develop antibodies against the baby. After the birth, a blood sample will be taken to test the baby's blood group. If the baby is rhesus positive, the mother will be given a further injection of anti-D immunoglobulin. (This is called postnatal anti-D prophylaxis.) Anti-D immunoglobulin will also given after any sensitising event that occurs during the pregnancy. Anti-D prophylaxis may not be necessary for rhesus negative mothers if there is certainty that she will not have another child following the pregnancy, for example if she is to be sterilised after the birth. It will also not be necessary if the father's blood type is also rhesus negative, as genetically this means the baby cannot be rhesus positive. Anti-D immunoglobulin may also be used if a rhesus negative individual is given a blood transfusion of rhesus positive blood, to prevent the individual forming antibodies against the transfused blood.

When I was in the 28th week of my pregnancy (in 1996) I was given the RhoGam injection. RhoGAM is a medical treatment that has nearly eliminated the risk of jaundice, hypotonia, and motormental retardation from Rh incompatibility between a mother and fetus. Rh incompatibility occurs when a woman without the Rh factor (a protein found on the red blood cells of most people), conceives a child who has the Rh factor. The mother's Rh negative blood will react against the Rh positive blood of her fetus and attack it with antibodies.

The RhoGAM injection halts the mother's immune system from responding to the Rh positive blood of her child as a foreign threat and attacking it with antibodies. RhoGAM is a preventive drug and in its current form offers huge benefits with very minor side effects.

I am also Rh Neg. 18 years ago I got pregnant my doctor at that time gave me a Rhogam shot immediately after learning my blood type. That pregnancy was successful and I have a beautiful 18 year old daughter. I had no complications. 18 years later my husband and I are trying to have a child. I have had two misscarraiges the first one was last March 2009, and the second one was yesterday Jan. 2010. I begged my doctor to give me the Rhogam shot at the beggining of the pregnancy for fear I would miscarry, however, he told me the shot is usually given at 28 weeks. I really feel my body has developed antibodies against anything foreign in my body. Is it possible to get any other type of treatment or shots or pills anything that will help my pregnancy be successful. Why can't I get the shot right when I get pregnant instead of 28 weeks? I really believe the reason I'm miscarrying is because my body is attacking the fetus. Please advise I want another baby with my husband.