The company "Hylands" makes a great RLS treatment ( they also make 'Calms Forte', a great herbal muscle relaxer/anti-anxiety pill). I have had RLS for about 15 years, and have been on all the Parkinsons drugs, Requip, Mirapex, etc, with horrible side effects. I could not deal with it,and saw this on drugstore.com, so I bought it ( it was super cheap, so I figured i had nothing to lose). It worked so well that I have not had symptoms in almost 6 months, and only once or twice in 2 years ( I used to have it every night, used to wear out the carpet pacing until dawn). The other great thing about it is that you let it disolve under youor tongue, so it works really fast. I think anyone with leg cramps or RLS/PLMD should try this..it is wonderful stuff! Hope this helps
I also found that taking Iron ( I take carbonyl Iron because I have animals around the house and regular iron is poisonous to them), and quinine from tonic water sometimes helps.
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