
Definition of Crohn’s disease Crohn’s disease, a disease named after the physician who first described it in 1932, is a disease that is closely related to the inflammation of the digestive tract. As ulcerations crohn's disease can affect any area of digestive tract, also called gastrointestinal tract, which is from mouth to anus, but is most common in the lower part of small intestine. The swelling extends deep into the lining of the ...